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Starting Hormone Therapy

Prostate Cancer | Last Active: Jul 4 2:49pm | Replies (37)

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Profile picture for jeff Marchi @jeffmarc

I am metastatic castrate resistant. I am on Darolutamide as are many other people I know that are also mCRPC. A lot of doctors don’t consider nmCRPC To be real. If you are castrate resistant, it is very likely you are also metastatic, If you can’t see it, it’s still too small to be seen yet.

Being castrate resistant is decided when your PSA starts to rise, even though you are on ADT. The only way your PSA is going to rise is if you have prostate cancer growing somewhere.

A huge number of doctors will prescribe this for you, If yours won’t, it sounds like you need to find a different physician. They will usually try to give you Enzalutamide, because some people on it have no side effect problems. You need to ask, saying Emphatically what you wish.

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Replies to "I am metastatic castrate resistant. I am on Darolutamide as are many other people I know..."

Thanks for the information--I am happy to hear that doctors will prescribe Nubeqa/Darolutamide for men who are castrate resistant in spite of what the official approval documents say. My husband finished Pluvicto in August 2024, and started Xtandi when the Zytiga stopped working after three years. The side effects of the Xtandi were so bad that he stopped taking it after about a month. We haven't yet asked the local (Indianapolis) medical oncologist about getting Nubeqa, but we see him on July 15 and will do so at that time. We also haven't asked Dr. Kwon at Mayo about it, but we see him in mid-September, and will ask him about it at that time, if not sooner via the portal, after we hear what the local medical oncologist has to say about it.