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Hormone Therapy

Prostate Cancer | Last Active: Aug 1 5:39pm | Replies (79)

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Thanks @brianjarvis The information you provided is helpful.
However, @lsk1000 you indicated in another discussion thread (Lupron, June 14) that you "don't think/don't know" if you are considered metastatic, and based on the description you provided, @northoftheborder replied on the same day, "No, you are not metastatic.
I noted that the "Doublet" Therapy OS benefits mentioned in the Phase III trial are for "mCSPC," or metastatic castration-sensitive prostate cancer -- a type of prostate cancer that has spread to other parts of the body and still responds to hormone therapy.
If I were you, I will ask my oncologist why I need double therapy when I'm not metastatic. I was Gleason 7 (3+4) on three of 14 cores, Gleason (0+2) on four cores, intermediate risk. I had 5-fraction SBRT in April 2025. My RO prescribed for me Orgovyx only. I'm on my fourth month now, RO said that we would see if I could get off Orgovyx after 8 or 12 months. I have read in some posts in this support group that six months ADT is about standard; I'm inclined to tell my RO that I want to stop ADT after 8 months, and not over treat.

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Replies to "Thanks @brianjarvis The information you provided is helpful. However, @lsk1000 you indicated in another discussion thread..."

Looks like you have a typo and I’d like to hear the right score

I am sure you didn’t mean Gleason 0+2. Was that supposed to be 4+3?

You wrote
“Gleason 7 (3+4) on three of 14 cores, Gleason (0+2) on four cores”

I’m going to be doing the 5 fraction SBRT salvage radiation soon. How did it go for you? My RO wants me to on ADT for two years, I’d rather do 6 months.