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Adverse Heart conditions from Hormone therapy

Prostate Cancer | Last Active: Jul 4 11:49am | Replies (23)

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Huh? I’m glad you are doing well with a single drug. My doctor (Mount Sinai) just prescribed Nubeqa + Orgovyx. I asked if I could take one or the other. He said studies show combinations keep PSA down longer and were overall better for long term survival. (If the side effects don’t kill you first).
He said combination therapy was the standard of care now. I wonder which way is better?

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Replies to "Huh? I’m glad you are doing well with a single drug. My doctor (Mount Sinai) just..."

The Embark trial studied Enzalutamide And Lupron. They wanted to find out what drug/combination worked the best. They found the two together worked the best, Enzalutamide Alone worked next best and Lupron alone worked the least best (Awkward). Doctors consider that Darolutamide Is similar enough to be substituted for Enzalutamide.

This was a case where the person could not handle ADT so a single drug that would work best seems to be Darolutamide. I say that based on a number of people I know over at Ancan.org That are using it standalone. It worked great for me while I was off Orgovyx for eight months.

The two together are preferable, according to that study.