I have been on ADT for almost 8 years. Orgovyx for the last year or so. Yes, you can expect brain fog if you stay on ADT long enough. It’s not just ADT, however, zytiga, apalutamide and Enzalutamide all can cause further brain fog. Darolutamide is the only one that doesn’t cross the blood brain barrier.

I have brain fog. I can’t remember the names of things, people just about everything, But it’s not like dementia. I find that I can use words to get around what I can’t remember, Though it will come back to me within a minute or two, most of the facts I know are clear as could be, Just don’t ask me the name of the doctor that told me those facts, most of the time. I can’t immediately remember the names of actors or politicians that I know very well, I will say a name one time and then it will not be there to say it again.

I have found you can get around this brain fog almost all the time. When I forget a word, I can describe the person or the object in great detail until I could find it on the web or somebody you can tell me the name.

It’s not like you lose your way home. You might forget the name of the street a block away, But that doesn’t matter because you know how to get home and most people can read a map To get street names if they forget.

The brain fog is more annoying than life changing.