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Share your test results (if you'd like)

Prostate Cancer | Last Active: Sep 24 5:49pm | Replies (121)

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"Your chances are much higher of getting castrate resistant PCa if you take it continuously."

I don't think the research has established that (yet), but it is a solid hypothesis. The thing is, there are basically three options:

1. if the cancer's not progressing, it's not progressing, regardless of what you're taking.

2. if it is progressing and you take ADT to shut down the castrate-sensitive cells, then the tiny minority of cells (if any) that are castrate-resistant may keep multiplying and eventually become dominant (though ARSIs like the -lutamides can postpone that, sometimes indefinitely)

3. if it is progressing and you *don't* take ADT, then the castrate-sensitive cells will remain dominant, but they'll still keep spreading because you're not doing anything to shut them down.

Neither option 2 nor 3 sounds great, but if option 2 gives you a lot more time before significant progression, that works for me.

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Replies to ""Your chances are much higher of getting castrate resistant PCa if you take it continuously." I..."

Totally agree 👍🏻

Your caveat “if the cancer is progressing “ is very important. Going off ADT when the cancer is not stable would be dangerous.