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Starting Hormone Therapy

Prostate Cancer | Last Active: Jul 4 2:49pm | Replies (37)

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Ask to switch to Nubeqa (Darolutamide). It works just as well and doesn’t have the fatigue problem that you get with Xtandi (Enzalutamide). I’ve been using it for a couple of years and I know a lot of other people using it and it works very well.

It also doesn’t pass the blood brain barrier, and therefore causes less Brain fog.

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Replies to "Ask to switch to Nubeqa (Darolutamide). It works just as well and doesn’t have the fatigue..."

My husband has metastatic castrate resistant PC, and it's my understanding that Nubeqa/darolutamide is only approved for non-metastatic or metastatic castrate sensitive PC. Pluvicto was only moderately successful for my husband, and his cancer is not back into remission. I am wondering what people have heard about next steps in treatment for someone in his situation.