← Return to PSE Test for Prostate Cancer Before an MRI and for Re-Occurrence
DiscussionPSE Test for Prostate Cancer Before an MRI and for Re-Occurrence
Prostate Cancer | Last Active: Jul 2, 2025 | Replies (49)Comment receiving replies
Replies to "thanks. while we are on the subject of PSA, should I use the standard PSA test..."
It is possible (but extremely rare, like "struck by lightning" rare) for prostate cancer to progress significantly without becoming detectable on the regular PSA test. So far, I have not found a single report of prostate cancer progressing without becoming detectable on the uPSA test.
As soon as your PSA is detectable, it doesn't matter which test you use — 0.7 means the same thing on PSA and uPSA. The only benefit of uPSA, as @jeffmarc mentioned, is earlier warning if something starts to happen. I never asked, and didn't even know I was on the uPSA test at first; I guess it's just the default for monitoring at my cancer centre.
Connect

That is a matter of your level of patience and anxiety.
I used the standard test for all of the monthly tests I’ve had for the last eight years. 15th year with PC.
We just had somebody come in this forum who was worried that their PSA had risen from undetectable to .02. These type of changes happen frequently, I attend weekly advanced prostate cancer meetings, where people come in and asking about very small changes in their PSA because they are using ultra sensitive tests. Usually, the PSA goes right back down and we don’t hear from those people about it again.
I myself don’t need that type of information after all this time. I’ve been undetectable for 19 months. That means I’m < .1. What matters is, if it ever exceeds that number, and does it for more than one month? If I had the ultra sensitive test, I might be freaking out about my PSA rising .05 to .07,. It can fool you into taking action.
So…..what is your level of anxiety about your PC.