@jcwest211 These are signs of an exacerbation - it doesn't really matter whether sinus or pseudomonas. It's time to contact your doctor before you have to wait through the holiday weekend and potentially end up in the ER.

This is a good reminder - anyone with a chronic lung disease who is susceptible to infections should work out an "emergency plan" with their pulmonologist.
The plan should include whether/when to "double up" on nebs and airway clearance, when to call them, and when to be seen immediately if your doc is not available.
Having a plan in place has kept me out of the ER, where unfamiliar docs nod their heads like they are agreeing with you, and then put forth an incorrect treatment.