I was diagnosed 50 years ago with System Lupus. In the 50 years I've only had 4 positive ANA titer tests yet I've had many flareups during that time - some very severe. I don't see medical doctors anymore - not for 20 years. I do holistic, naturopathic and Asian medicine - it has saved my life. I went to the Mayo Clinic in 1998, and after 2 weeks of testing, etc. they told me to stay away from the medical community unless it was an emergency, they told me to go all holistic, eat clean and take good care of myself. They said the doctors would kill me trying to save me. I took their advice, and while I have occasional flareups, they are few and far between. I eat all organic, do liver and kidney cleanses every 90 days and take supplements. 2 years ago I ended up in the ER with high blood pressure from a flareup - the doctor insisted I had kidney damage because first of all, no one lives 50 years with lupus, and second of all since I have there is organ damage. I made him run the tests while I was there, and he came back in and said he couldn't believe that all my tests were normal - he called them beautiful. There's a lot to be said for holistic- I'm living proof. I hope this helps.