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Prolia vs. Evenity

Osteoporosis & Bone Health | Last Active: 3 hours ago | Replies (21)

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@hollygs

I was on Evenity for one year. I tolerated it very well - no issues whatsoever. DEXA and TBS showed good gains. My journey with osteoporosis meds is on this site under "Prescribed Tymlos after Evenity."
I was in the same boat - after finishing Tymlos I needed a new doctor and felt anxious about the timeline. Then I dialed back on the anxiety because I absolutely know that stress is terrible for my health and I don't want it in my life. I found a doctor who agreed to meet with me on a video conference the next day even though the usual wait for an appointment was 8 months. So I got lucky. Very lucky. I finished Tymlos 3/15/25 and my Reclast infusion was 5/12/25. My doctor put me on a drug holiday because I had been experiencing extreme fatigue and joint pain, and she thought it might be from the Tymlos and wanted my system to calm down. She was right as the fatigue and joint pain were gone in a month and haven't returned.
You're absolutely right that you can't foretell how you'll react to any drug. You've obviously educated yourself thoroughly. I will say that when I relaxed about the whole thing, I found it easier to tune into my intuition about what I should do. What I see from what you've mentioned is that your cardiac condition is stable and you seem to be more concerned about your autoimmune disorder.
Do let us know how you get on and what you discover.
Best wishes to you moving forward.

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Replies to "I was on Evenity for one year. I tolerated it very well - no issues whatsoever...."

@hollygs, thank you once again for your kind response. I am having a heck of a time finding an expert anywhere in the whole state of Texas who is not booked through June of 2026 where new patients are concerned. Were you an established patient with the wonderful doc who gave you a quick video visit? Some I've contacted won't do telemedicine with a new patient, and if you were a new patient with this doc, please tell me how you convinced him to see you! 🙂

I am stressing something awful over this, which I know is so counterproductive and unhealthy. Today, the endo who originally said she'd prescribe Evenity backed off from that, and my rheumatologist is discouraging me as well. They will give it to me if I truly want it, but at the same time keep telling me "the standard of care is NOT to prescribe Evenity to anyone with a cardiac issue." When I bring up the contradictory study results (re: cardiac events with Evenity), they acknowledge them. But because the "standard of care" rules have not officially changed, I am being left on my own to choose. Enormously stressful and frightening

I am considering doing what they would like -- a Prolia injection -- just to buy myself some time to find a real expert. But am not happy about that at all.

In any case, thank you for listening to all this, and thank you for understanding what a rough go this can be! I wish you all good health! 🙂