61 years old with MDD and anxiety (PTS). Over the past five or six years I have been on varying doses of (one medication at a time):
Lexapro
Duloxetine
Fluoxetine
Bupropion
And now I have been on Auvelity for the past six months.

Some have worked, some worked for awhile, and one had a very negative side affect with my HOCM. The thing they all have in common is I have neither cried nor felt joy while taking them. I'm signicantly less depressed, but I'm stuck in the mid-range emotions. Trying to expand my emotions beyond flat is the main reason I have been chasing the right medication in the right dose.

Auvelity brought the most dramatic increase in my mood level than the any of the others.

In May, I completed Transcranial Magnetic Stimulation (TMS) for depression and anxiety. What a difference it has made. Prior to TMS, even on Auvelity, I didn't want to get out of bed. Now I'm a functioning member of my family!

TMS works for some and works for different lengths of time. The psychiatrist recommended I not change any medications for a year (also taking trazodone and serequel at night) so I am keeping my fingers crossed that when I can stop taking auvelity, I will regain my full range of emotions.

All of that to say I have had a positive experience with Auvelity.