Thank you for joining this forum, especially on behalf of your husband. My wife has been my hero through doctor appointments, radiation treatments, and hormone therapy, along with my trying to change diet. I was diagnosed at Thanksgiving with Gleason seven (4+3) and regional risk with spread to two lymph nodes near the prostate. I have not had surgery, but have been taking Orgovyx for six months and am two months past 44 weekday radiation treatments that included concentration on the prostate and across the pelvis, generally. You have a right to be afraid; cancer is a scary word no matter which label is placed in front of it. I highly recommend if your husband will be on hormone therapy while he is taking radiation, that he talk with his supervisor about moving to part-time work or having the flexibility to take extra time off. I’m retired, but a friend who is 67 was taking radiation at the same time that I was, and while working full-time was completely miserable. He arranged to take an extra day or some extra time off. I suppose I was one of those special cases in that I experienced Every side effect that was listed on the Orgovyx manufacturer website including hot flashes, fatigue, loss of libido, ED, weight gain, and diarrhea. I agree with everyone here that exercise helps combat fatigue, and I try to exercise every weekday, but no matter what I do it’s as though I’m a car with all flat tires in the afternoons. If your husband is not accustomed to resistance training, he might do as I did and meet with a personal trainer for a few sessions to set up a program of upper and lower body exercises. he may not be old enough yet for silver sneakers through Medicare, but I believe planet fitness offers fees as low as $10 a month for basic access to fitness equipment. My energy has improved a bit starting several weeks after completing all radiation treatments. My PSA has gone from 6.4 last August to 0.01 this May. Prayer for clear direction going forward and excellent outcomes!