It just depends on how fast your adrenals recover. Assuming that Actemra is controlling the inflammation part then it is more about how long it takes for your cortisol level to rebound. I’m not telling anyone what to do. Actemra was a game changer for me. I tapered by 1 mg per week from 7 mg to 3 mg. When my cortisol level was low I stayed on 3 mg for 6 months before tapering of prednisone completely.