← Return to Statin discontinued due to neuropathy. What are some alternatives?

Discussion
Comment receiving replies
Profile picture for vogie @vogie

I am a 69 year old female who has always had a normal BMI and a good fitness level. My labs have always been completely normal except for the lipids. I am on the athletic side. I am a life long exerciser. The only prescriptions I have ever taken on a regular basis are for HRT, which I started in my early fifties and continue to take.

I have resisted my doctor's urging me to take statins for years, as I have very high cholesterol. Male family members have taken statins and continue to take them while enduring long term muscle pain and muscle wasting. My father died at 53 from a heart attack, and his father at 60-so I can understand their risk/benefit analysis.

I was finally bullied into starting statins by my husband and several doctors last year. I started Rosuvastatin in March 2024 and experienced crippling muscle pain in my legs the following summer. I was eventually switched to Atorvastatin . Within 2 weeks of starting this statin I developed neuropathy in my hands and feet which greatly interfered with my sleep. On one day only, I experienced the tingling all up and down both arms and legs as well. This was a ghastly and very frightening experience. The neuropathy has been intermittent since, and limited to my hands and feet with an odd shooting tingly in other random spots, very occasionally.

Doctors dismissed the muscle pain and the neuropathy as extremely likely to be unrelated to the two statins. One said that there is absolutely no evidence that either statin causes these conditions. I feel like I am being gaslighted.

I discontinued the second statin. I was also starting to see my glucose numbers rise, but they were still in range

Now I am taking Repatha for cholesterol and gabapentin for the nerve pain. I see a neurologist for the nerve pain and will be undergoing further testing. She prescribed the gabapentin. I am taking 300 mg at bedtime. The worst side effects from these are fatigue, though I do get tremendously good sleep since starting the gabapentin-which is why she prescribed it. The gabapentin makes me very relaxed and limits my interest in exercising, although I am much calmer and less type A than I was prior.

My glucose A!c hit 6 on my blood work last week. I was consistently in the mid 5s for many many, years prior to starting stains and Repatha. I have read that medication induced diabetes may be irreversible, and I find that very scary. My energy levels are quite low and my weight has been rising rapidly. I am up from 135 to 153 since March 24. I am 5'2. None of my clothes fit and my lifelong motivation to exercise has waned.

Now the doctor in cahoots with my husband are recommending Zepbound for weight loss and blood sugar control.

I am thinking I would rather stop all these medications and just live with high cholesterol.

Anyone with similar experience?

Jump to this post


Replies to "I am a 69 year old female who has always had a normal BMI and a..."

Hello @vogie,

I see this is your first post on Connect, welcome! I have taken statins for at least 20 years now and put if off for several years before then. My lipid numbers were generally well controlled. However, two years ago, my triglycerides jumped up over 300, and my doctor and I were surprised. Like you, I have a BMI of 23, and there had been no change in my lifestyle (eating, exercise) as well as no change in stress levels (stress can play havoc with all of our bodily systems).

So we tried adding a new drug, which resulted in too many side effects. The cardiologist then prescribed a prescription-strength Omega-3 drug called Lovaza. My prescription plan did not cover it; however, I found it on GoodRX for $40 a month. After one month of use, my doctor ordered lab work. My triglycerides, which had been over 300, were now in the range of 100's. My cholesterol had also dropped about 100 points.

While we all react to medications and supplements differently, you might request a prescription for Lovaza to see if it would help you. I'd love to hear from you again. Will you post updates as it is convenient?