I will add two things in addition to what the others have said:

If your husband *DOES* get the depression side effect, take care of it sooner rather than later. I waited too long out of male pride and suffered much more than I had to.

If maintaining a sex life is something important to you, see a sexual health doctor. Obviously, it's not as important as eliminating the cancer but hormone therapy will generally lower or eliminate libido. Mine put me on two years of low-dose Sildenafil (Viagra) to keep blood flow and prevent atrophy (use it or lose it). He'll also want to induce erections at least 3x a week since the normal ones that occur when men are sleeping will go away.