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Vitamin B6: pyridoxine hydrochloride vs. pyridoxal 5’-phosphate?
Neuropathy | Last Active: Jun 29, 2025 | Replies (20)Comment receiving replies
Hi thanks for answering. Yes, now I avoid ALL forms of B 6 but not sure if the B 6 in EB N5 is the same? It is called P5P. I believe the Smarty Pants gummies and other supplements have caused the toxicity, However, I was told I would get relief from neuropathy from P5P in the food-medicine called EB N5 (It contains other nutrients)
Thank you for your caring words!
Replies to "Hi thanks for answering. Yes, now I avoid ALL forms of B 6 but not sure..."
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Good morning miacrab (@miacrab)
I'm the fellow who posted the original message way back in 2023. Since then, I've been gathering as much information as a layperson possibly can about the distinction between B6 pyridoxine hydrochloride and B6 pyridoxal phosphate (P5P). I've been doing this because, on the suggestion of my neurologist (who is also a physiatrist), I've been taking EB-N5 –– or, I should say, I had been taking EB-N5, now almost two years' worth. Only last month, this same neurologist asked if I might be willing to switch to a slightly different formulation: EB-M8. I've only started taking EB-M8, so I'm unable to give it a grade: 1 for it's doing me harm, 10 for it's the miracle cure we've all been waiting for. Right now, EB-M8 is a ?. I suspect it'll remain a ? for quite some time. As I written here before, with regard to EB-N5, it, too, remains a ?, but that is to say: it does not appear to have done me any harm. In fact, my PN (chronic idiopathis axonal polyneuropathy, or CIAP), whose chief symptom is poor balance (no pain), does not appear to have worsened in all these months, or if it has, it has worsened only microscopically.
My best wishes to you, miacrab, al to all PNers!
Ray (@ray666)