I use clobetasol ointment when I have flare twice a day for a month then once a day for 3 weeks then I go to twice a week for maintenance. I use estradiol vaginal tablets twice a week. I have found if I am doing something to sweat a lot like gardening I come in take a shower and apply clobetasol ointment helps from getting flares. This seems to be keeping my flares under control and life more bearable with awful condition. I tried to use estrogen cream, but it set me on fire and made my skin worse but with vaginal inserts I am 100 % better. I hope this helps you. I have had this for 14 years and this is the therapy I used, and I haven't had a flare for over 6 months