EPE can be identified during radical prostatectomy or sometimes preoperatively through imaging like MRI. That is how it can be removed during surgery. The clean margins showed that they did get everything that was there at the time.

If it is In your bloodstream you want to be on Something like ADT to prevent it from growing. Has the doctor mentioned you need to take ADT?

The presence of EPE can influence treatment decisions, potentially leading to recommendations for radiation therapy (following surgery). In your case with the clean margins, ask your doctor if that is necessary. Depending on the state of the EPE, it is possible it got into the bloodstream. You can do something like a PSE Test to see if cancer is actually in the bloodstream. You could ask your doctor about this test.

This was posted by an Episwitch representative
Just to clarify, the EpiSwitch PSE test analyses immune cells in the blood that have been at interplay with prostate cancer (or not). Your PSA value only makes up a small portion of the results of the test. There are other very informative biomarkers assessing the presence or absence of PCa included in this test. So yes, EpiSwitch PSE can still be used with a very low PSA score, and can still detect prostate cancer without PSA shedding. Therefore, the test can be used before, after and during treatment - even after complete prostate resection. In your case, a 'low likelihood' result could potentially help you avoid things like PSMA scans if your PSA indeed rises over time. A 'high likelihood' result could be indicative of recurrence, irrespective of low PSA."