Oh yes. Every level of anxiety, panic, uncontrolled anxiety and panic = "going off the deep end" aka "severe panic episode with psychosis related to stress and anxiety".

No one ever wants to experience a psychotic episode related to anxiety and panic. It nearly killed me it was so bad.

I have also had anxiety and panic to the point of having to be hospitalized in an ICU for blood pressures of 110/190+ .

There are medications that can prevent a stroke in the making and a BP of 110/190 is life threatening, panic and anxiety can kill you if it is uncontrolled.

Fortunately for me, I have very good heart function. I have some impairment of kidney function due to panic and anxiety raising my BP when the panic and anxiety is uncontrolled; therefore I am on panic/anxiety BP meds to control any increases in BP due to random anxiety or panic attacks.

When panic and anxiety are uncontrolled the brain checks out. That is what happens and it was such a traumatic experience for me that I then lived with the fear it would occur again. Once I read, learned and was taught by competent medical personnel, I learned to recognize, control, and treat myself at the onset.

I learned to do the same with depression, but that was much easier to control as depression does not kick in the flight or fight physiology which is very hard to control if one does not know how to do it.