I’ve had PC for 15 years and been on hormone therapy (ADT) for eight years. It’s never really changed my life, There are some things I have to do to offset it, But it allows me to stay alive.

Your husband’s case could be very treatable. I know many people with Gleason 8 that have lived decades without problems. Getting the proper treatment, which in this case almost always includes ADT, stops the cancer from growing and shrinks it so it can be treated more easily. If you work with a center of excellence and/or a Genito Urinary Oncologist You will get the best treatment. In this case, I would recommend a second opinion from somewhere else because this is a serious case that needs to be treated properly. Get a second opinion to make sure what you are hearing is confirmed by other doctors.

Due to their different mechanisms of action. ADT which includes Orgovyx, Firmagon, Lupron, Eligard, Prostap, Camcevi, Lucrin, Zoladex, Trelstar, Pamorelin, and Decapeptyl can cause numerous side effects. Actually due to a lack of testosterone.
Hot flashes
Fatigue
Muscle deterioration
Bone weakening
Brain fog
Depression
Weight gain
Difficulty in breathing

Not all of these side effects occur to everyone on the drugs. Most of them are just things you have to be aware of and circumvent. I walk on the track twice a day, 1 mile at least, to help prevent bone weakening, fatigue and muscle deterioration. I also go to the gym three days a week (usually) and spend an hour with all different types of weight exercises. One thing that happens as people get a beer belly from the muscle deterioration, I do a lot of sit-ups to offset that.

Some people get depression but it is not common. It is easily treatable, according to people that have reported it on here and on Online Meetings I have participated in. If he has that problem Come back and ask for help, Or see a psychiatrist about doing something to relieve the depression.

When I first started ADT I got a lot of strong hot flashes. Some people get none at all. Others only have a few hot flashes and they are very minor. If you have a problem with hot flashes, you can come here and we can give you help to resolve them.

According to a doctor that spoke to a recent webinar, all people on ADT should be taking bone straighteners. I took Fosamax for six years and I’m now on Zometa. That along with calcium taken daily helps keep your bones strong. Ask your doctor about this.

I have never gained any weight while on ADT. I get on the scale every morning and base what I eat on what I weigh. Skip lunch at times.

Isn’t thyroid cancer resolved by removing the thyroid and taking a once a day pill? My wife had problems with her thyroid and they told her that might be something she would have to do. Just asking for possible future issues.