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New Pancreatic Cancer Diagnosis

Pancreatic Cancer | Last Active: 5 hours ago | Replies (37)

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@gamaryanne

@mcharlesfrancis
Thank you for posting this!
Can you share the mutations(if any) they found ?

@mnewland99
Thank you for mentioning TP53 and paclitaxel. I know there has to be a relationship between the mutations and drugs that take longer for resistance. I’m on the 3rd (standard of care) and don’t want to misstep in my next treatment plan. It’s a journey, isn’t it? Always trying to stay one step ahead, since our doctors seem to only be tasked to keep us alive one more day. Praises for those specialists that sincerely see this as becoming a chronic condition.

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Replies to "@mcharlesfrancis Thank you for posting this! Can you share the mutations(if any) they found ? @mnewland99..."

@gamaryanne it is certainly a rocky journey! Nerve racking as I feel tasked with choosing the treatments I must take to try and extend my life. Thank goodness there are so many courses to choose from. I hope you are doing well. My task is difficult as due to my underlying arrhythmia that arises following stress to my body and breathing difficulties I've had since 5 years old that made my Naliri chemo very difficult for me. I'm waiting now to get CT of lungs to see whether I had changes to the existing scar tissue in my lungs versus an allergic reaction to the Naliri. I had to find, on my own initiative, a potential alternative. I have appt with IR to ensure whether histotripsy is still an option given the number of lesions I now have in the liver and I'll have appts with oncologists at St. Jude and UCLA to see if I'm a candidate for a clinical trial to receive a combo of Zolbetuximab and 5FU. It is for those that have the CLD18.2 protein which I have. It's a Phase 1. I like this one because Zolbetuximab has already proven a worthy opponent for peritoneal and stomach cancer and 5FU kept me with low cancer antigens (CA19-9) while I was on it. My observation is that abraxane works well for liver metastasis, but it's rather potent and caused neuropathy when I was on it, so maybe histotripsy will at least get rid of my present liver lesions. It's an incredible journey and you've been so proactive medically and active in your personal life - a path I try to emulate. God bless everyone on this forum and all the researchers and drs we place our care in.