That would be my concern, too. I’m just so tried of making my body an experiment lab. It seems some of my side effects from Repatha and statins have never gone away. I get so sick and the recovery from these drugs takes longer and longer.

Heck yes I was concerned about 6 months, @repathaconcerns! On the flip side, I was excited at the idea of going to someone else who gives the injection taking patient compliance out of the realm of possibilities.

Before starting:
-I found a doctor I trust that understands the available drugs as well as my unique needs.
-I was following a consistent heart-healthy diet, exercise and strengthening activities.
-I had a conversation with my pharmacist.

I learned Inclisiran stays in your body for about 2 days. It is a small interfering RNA (siRNA) that is gene silencing. I don’t necessarily know more about this except it works differently than any other cholesterol drugs. Do tell if you have learned more!

I had a bad night the night following injection #1, a little better than bad night the 2nd night following injection #2, an inconveniencing night the 2nd night after injection #3. Disclaimer: I am used to bad nights so am a bit hesitant to say the drug caused problems. Maybe it helped?

I have been taking it for over a year and no leg or knee pain.