← Return to Switching from Orgovyx to Bicalutamide

Discussion

Switching from Orgovyx to Bicalutamide

Prostate Cancer | Last Active: 3 hours ago | Replies (13)

Comment receiving replies
@kenk1962

Hi Jiime - do you have any insights on why Dr. Hugec's patient has a total testosterone of 1100 while using Darolutamide, an androgen receptor antagonist? A 1100 ng/dL level is quite high and suggests the patient is receiving testosterone replacement therapy (TRT).

I haven't heard of these two being used together. I'm thinking Darolutamide and TRT would likely oppose each other.

Jump to this post


Replies to "Hi Jiime - do you have any insights on why Dr. Hugec's patient has a total..."

He says he's only receiving the ARPI which allows Testosterone to rise while keeping the cancer cells from feeding on it (Androgen Receptor Pathway Inhibitor). His recurrence in three lymph nodes has disappeared, avoiding additional treatment for now.