Tymlos at 70+ - Pros & Cons with severe osteoporosis

I, too, am about to turn 70. I decided, at the tender age of 68, that compression fractures (I've had four since 2017), and the debilitating effects we may suffer from them were riskier than the meds and chose to begin Tymlos, followed by Evenity and then Reclast. For the record, I did not tolerate Tymlos well and was only able to make it to about 9-1/2 months, but I've had Reclast infusions, off an on without any side effects since about 2011, and depending on what my rheumatologist says, I will have another infusion in July/August of 2025. Evenity and Reclast were easy-peasy for me.

Talk to your doc, do research, and decide what's best for you. Remember that we are all different and a med that works for one may not work for all. Listen to your body and advocate for your health. I tried to tell my doc that Tymlos was causing my grief, but he replied with "that can't be, none of that is listed on the website as an adverse reaction." Piffle! Best wishes to you as you make your decisions!

Cheers! Happy Spring!

What were your side effects? Please share with us, I am new on Tymlos only one month. I am researching still about people’s comments and found getting a belly fat on some of patient. Please you share your feedback about Tymlos, why You discontinued it? I know the common side effects are nausea and dizziness that when you inject at night before your sleep, you won’t feel any nausea. Thank you I am looking forward to hearing from you.

Hi @npoursafar,

On Tymlos, I had many adverse reactions. I injected in the morning and at night - I couldn’t escape the nausea, even with Ondansetron (my doc couldn’t believe it didn’t help).

I also had severe shoulder, back, and chest pain, the “broken ankle” feeling that others report, racing heart (+120 at times). If I think about it, I’m sure I’ve forgotten a few. I continue to have a jelly roll around my middle that I didn’t have before Tymlos.

This medication didn’t work for me, but it obviously works for others. I did have excellent t-score improvement, but my DEXA was after 9-1/2 months of Tymlos and about 6 months of Evenity so I’ll never know which med worked for me; perhaps it was the right dosage/right sequence for my old bones 😉.

Cheers!

For me it’s worth a try to avoid compression fractures. I haven’t had a dexa yet to check on progress. I’ve been on Tymlos for 5 months and doing fine. Decided to start at 1/4 dose and work up to full dose. My Dr said Tymlos works better if you didn’t take a bisphosphonate first . Best of luck to you

I personally would not recommend Tymlos OR Fortea to anyone based on the severe side effects (and minimal positive results) I experienced first hand.
The racing heart, breathlessness and nausea were horrible, I HIGHLY RECOMMEND taking Citracal as that gave me the BEST results of anything and everything I’ve tried including Osteostrong x years….
Why are they suggesting Reclast infusion if your T score hasn’t been addressed, or improved, first???

I personally would not recommend Tymlos OR Fortea to anyone based on the severe side effects (and minimal positive results) I experienced first hand.
The racing heart, breathlessness and nausea were horrible, I HIGHLY RECOMMEND taking Citracal as that gave me the BEST results of anything and everything I’ve tried including Osteostrong x years….
Why are they suggesting Reclast infusion if your T score hasn’t been addressed, or improved, first???

So, because you had side effects, nobody should take those medications? A calcium supplement is not going to do anything special.

Here, I'll turn it around: I am in my 15th month on Tymlos, and my osteoporosis is now osteopenia, and I had NO side effects. I personally would recommend it to anyone.