My one a day multi had 75 mg of b6. When i started on vitamins and alternative health in 1997, and all the reading from dr.s using alternative treatments, i looked for vitamins with at least 50 mg of b's. so many only have 2 mg......i guess they are using RDA, but, RDA has everything too low. Check out NATIONAL INSTITUTE OF HEALTH WEBSITE ......in google, type in is B6 toxic, and of several websites , that one will pop up, and give you some info. it says rare cases of toxicity at 500 - 1,000 mg of b6. But very saft under 200 mg. Silly thing, i thought, about 20 yrs ago, my toe curved and wouldn't straighten out. after a few days, i saw my naturopath Dr., who said........take b vitamins. I said my multi has it, she said, well take extra. So, thinking that was the dumbest thing i ever heard for a crooked toe, i got a bottle of 50mg b complex.
So, now i had the 75 mg in my multi, plus 50.........Boom,, the next day, my toe was back to normal............For a few years, i was using at least 100 mg of b complex............after over 25 yrs of using alternative things, not just vitamins/herbs, but many other things , at 82, i am on NO drugs, NO surgeries. So, for me, the higher doses of B vitamins, did no harm. We are all facing a puzzle, with the problems we all have, trying to figure out what to do. so every piece of info we get from each other helps up with our personal puzzle, to see if that bit of info fits our scenario. Somehow, i dont' think we will ever get the 1,000 piece puzzle together, but, every little bit gives us a better picture. this wasn't very helpful, but, it is just one more piece of your puzzle.........maybe helped a little. Check out National Inst for a little more infor.