Hey there, I was diagnosed with Stg IV Melanoma five+ years ago which led to surgery(removed original site on shoulder and lymph nodes in armpit) and immunotherapy. The drugs I took were Ipilimumab(Yervoy) and Nivolumab(Opdivo) concurrently for three times(three weeks apart), I was unable to take the last recommended dose. After that there was a brief pause due to side effects and Covid hysteria( it was March/April of 2020 ) and I continued with Opdivo for almost three years. At the time Yervoy/Opdivo combo was pretty much the only good option for StgIV but maybe that’s changed since then, I know they were looking at targeted therapy(forgot the name since I never ended up doing it but it worked on a gene mutation with the BRAF gene) as an option. Anyway, the side effects were quite a bit more severe for me with YervoyOpdivo together vs just Opdivo. You didn’t say which names so it could be a different scenario. There used to be a melanoma specific forum that had several people with immunotherapy histories that was pretty informative but i haven’t been doing any of that for years now. I feel like I wouldn’t be alive now without that course of treatment but you’re Stg III so may have a different regimen.