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Implications of Long Term Drug Regime

Chronic Pain | Last Active: Jul 2, 2025 | Replies (21)

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GabaPentin and PreGabalin are both related to the amino acid GABA gamma-aminobutyric acid as you might surmise since they both have GABA in their name. GabaPentin was useless for me, but PreGabalin is in wonder drug category.

RE: Naproxen.
from
https://www.google.com/search
"Yes, naproxen, a non-steroidal anti-inflammatory drug (NSAID), can potentially damage your kidneys, especially with prolonged or high-dose use. Naproxen can lead to acute kidney injury (AKI) or worsening of chronic kidney disease (CKD). "
https://www.google.com/search
Lyrica aka PreGabalin and your kidneys
https://www.google.com/search

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Replies to "GabaPentin and PreGabalin are both related to the amino acid GABA gamma-aminobutyric acid as you might..."

I absolutely agree about the efficacy of PreGabalin. I had major thoracic surgery for severe pain and numbness from my right buttocks down to my right foot. That back surgery worked wonders almost totally eliminating the pain and numbness. That lasted about 10 months and then the numbness came back with a vengeance (no pain though- thank you, thank you, thank you!) Pain management then suggested PreGabalin, and on the second day of its use the numbness was reduced 50% in both intensity and duration, and no noticeable side effects! It also greatly elevated my mood, which had suffered because of dealing with too many unexpected and serious medical issues in a few short years (been healthy all my life so I am kind of a baby when I get sick). Perhaps it doesn't work that well for everyone, but for those that it does it is a blessing!