Before going on fosamax did your doctor check the reason for your osteoporosis? Parathyroid, kidney, nutrition deficiencies?? From reading Great Bones by Keith McCormick (and listening to many YouTube information about osteoporosis meds), I understand that Fosamax should give you a better bone density by inhibiting Osteoclasts cells from working (the cells that destroy bones). Maybe fosamax didnt work because the Osteoclast cells (the cells that break down bones) that fosamax inhibits from doing their job are not the culprits. Did your doctor check your CTX levels before, at 3 months, 6 months etc? No need to wait for 2 years to check if fosamax is working. Ask your doctor to do a blood work and check your CTX levels. If they are coming down, then fosamax is doing its job and your bone density should be getting better. If your CTX is down but your bone density is getting worse, then there is something else going on. Good luck!