Hello Bruce, my father was on docetaxel, so i wanted to share his story as a warning because docetaxel has serious, life-threatening side effects. He was diagnosed in 2020, Gleason 4+3=7, locally advanced. He was on injections plus radiation, then later abirateron when injections failed, and then about 6 months ago his PSA started raising again, so he was offered docetaxel (at least one dose) after which he would get 6 cycles of Pluvicto (for which he was an ideal candidate-all mets showed score 3). After first round of chemo his PSA almost halved (from 128 to 72) so doctor decided to include 2 more cycles before Pluvicto. My father died from sepsis 10 days after receiving his second dose. Not once were we informed that this might happen. The only thing he complained was lower back pain which which started 3 days after the second dose and was progressively getting worse. The oncologist discarded it as pain from metastasis in his spine (which he did have, but never bothered him until he started chemo) and gave him stronger pain killer. No fever, rash, burns when i pee complaints, it just jumped from extreme pain to loosing consciousness. When i called ER, their first diagnosis was dehydration, then heart attack, and finally after 4 hours-sepsis. His CBC was completely normal (except mild anemia), but his CRP and procalcitonin were off the chart! Unfortunately even though drug comes with a warning that sepsis is a possibility, patients only get CBC checks when on chemo (at least in my country). My father didn't have to die, he is a victim of under-educated doctors and drug that don't come with proper instructions! PLEASE check CRP and procalcitonin with your CBC when on chemo, stay away from crowds (no gym) so that you minimize your exposure to bacteria, and if you notice any side-effects immediately go for a check-up! We were told that with chemo and pluvicto he would be in remission for 3-5 years, and he died 2 months after. I blame myself for convincing him to accept the treatment. He would still be alive if we declined (we were told 2 years with no further treatment). And the worst part is that his cultures came back 3 days after he died and they weren't able to identify the bacteria, so i don't even know what killed him! Please take care of your self and best of luck!