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Implications of Long Term Drug Regime

Chronic Pain | Last Active: Jul 2, 2025 | Replies (21)

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No. The doc wrote a Rx for GabaPentin and that was that. At the time, we never heard of GabaPentin let alone Pregabalin. They sound like they’re from the same family so is there a difference? Another question that I had, I don’t think has been addressed fully yet in this thread. Are the kidneys / liver capable of handling chronic dosing with Tylenol 3 / Naproxen without significant damage?

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Replies to "No. The doc wrote a Rx for GabaPentin and that was that. At the time, we..."

GabaPentin and PreGabalin are both related to the amino acid GABA gamma-aminobutyric acid as you might surmise since they both have GABA in their name. GabaPentin was useless for me, but PreGabalin is in wonder drug category.

RE: Naproxen.
from
https://www.google.com/search
"Yes, naproxen, a non-steroidal anti-inflammatory drug (NSAID), can potentially damage your kidneys, especially with prolonged or high-dose use. Naproxen can lead to acute kidney injury (AKI) or worsening of chronic kidney disease (CKD). "
https://www.google.com/search
Lyrica aka PreGabalin and your kidneys
https://www.google.com/search