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Salvage radiation decision: with or without hormone therapy?
Prostate Cancer | Last Active: Jul 30 6:54am | Replies (58)Comment receiving replies
@jaacm1 You mentioned you have manageable incontinence and ED. I also have these issues following RP surgery and I never fully recovered. As I'm considering ADT, I've read that it could have significant side effects regarding incontinence and ED. Was your incontinence and ED a result of your RP surgery, or did it happen after starting Orgovyx? If it was a result of RP, did it get worse after starting Orgovyx?
Replies to "@jaacm1 You mentioned you have manageable incontinence and ED. I also have these issues following RP..."
ADT reduces testosterone levels, and androgens play a role in maintaining the strength of pelvic floor muscles. When these muscles weaken due to ADT, it can lead to urinary incontinence.
The ED problems occur after surgery, The ADT drugs take away the desire, Which can’t affect the ability to get an erection, But the real problem is that many men after RP just can’t get it up without assistance from drugs or a pump.
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Chuck, I was able to overcome my incontinence after RP by doing kegels. Regarding ED, I was ok (needed a prescription) after RP but not 100% the same as I was heading into the procedure. Orgovyx worked well on me and lowered my T from over 600 to almost nothing. For the 6 months I was on the drug it eliminated all interest/ desire. When I came off the Orgovyx and had gone through SRT, the desire returned but I still need a pill. That said, the combo of the hormone and the SRT definitely negatively impacted me as compared to where I was pre-RP and post RP. My T is over 500 last time it was checked.