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Intermediate Risk Prostate Cancer Treatment Decision

Prostate Cancer | Last Active: Jul 11 11:25am | Replies (53)

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Profile picture for matthewdore @matthewdore

tk192,

OK, good luck in FL. .

I have a video call with Mayo MINN tomorrow. I'm not sure what types of Focal Therapy they do................HIFU, Tulsa, Cryo??? I have researched them all. But my first question will be" Does the high decipher score point you to certain therapies or are Focal options still on the table?
Second question: what are long term probabilities of recurrence for Focal Therapies? My research shows (approx. ) 25% recurrence with Focal vs. 6% recurrence with Radical Prostatectomy and Radiation. I'm going to ask Mayo if there is any way to get that 25% number lower. Age, health, family history, MRI/imaging advances, ......... etc.

Third question: If recurrence, ........ex. after 4 years, .........will the recurrence be in the prostate or will it have spread to outside the prostate? Is that where the Decipher score is telling? That is the big question.

Good Luck again,

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Replies to "tk192, OK, good luck in FL. . I have a video call with Mayo MINN tomorrow...."

My research indicates recurrence rates for RP at 5 yrs 10-25%, double that for 4-3 Gleason vs 3-4, 10-20% for radiation but half that with ADT hormone therapy added, Focal therapies are 20-30%. All of these have similar outcomes at 10 years add 10%-15% to the 5 year risk rates, but some focal therapies don't have 10 year results yet (Tulsa). My call with Mayo nurse is tomorrow. Meeting doctors 26th.

Good luck

Shared files

Tulsa Pro TACT Trial_5-year Interim (Tulsa-Pro-TACT-Trial_5-year-Interim.pdf)

Tulsa Procedure 4 (Tulsa-Procedure-4.29.2025-CAPTAIN-PRESS-RELEASE.pdf)

If you are able to get answers to your questions if you would, please share with us what you were told. You have some very good questions. I had TULSA-PRO at Mayo in Rochester in October 2024. These questions apply to me as well. Thanks much!