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Switching from one GLP-1 RA to another?
Bariatric Surgery & Weight Loss | Last Active: Sep 28, 2025 | Replies (32)Comment receiving replies
I was on Ozempic for a year and lost 110 pounds. I felt like after a year, I started to plateau and wasn't losing weight. The food noise started again. I talked to my doctor and she switched me to Mounjaro. From the time I quit Ozempic and am currently on 10 mg and am not feeling any difference in the noise. I've gained 45 pounds back in 2 months from the switch. My doctor is not very supportive and tells me to be patient also. I don't know how much longer I can hold on for the Mounjaro to start working for me. I am very frustrated and feel my doctor is dismissing my frustration. Any advice would be so appreciated. Thank you!!
Replies to "I was on Ozempic for a year and lost 110 pounds. I felt like after a..."
As I understand it. Ozempic for diabetes opposed to using Ozempic just for weight loss is absorbed in our bodies differently. I’ve been on Ozempic since it first came out for Diabetes. My numbers are awesome. I lost maybe 15 pounds and I stopped losing. I haven’t gained, but, maintained my weight. I know and have to be on Ozempic for the rest of my life for Diabetes. Ok. From what I understand if you use Ozempic strictly for weight loss, the pounds just slide off. The unfortunate part is, that you need to continue taking Ozempic for the rest of your life to maintain your weight. A lot of people get to their desired weight and go off of Ozempic. Wrong. Statistically you will gain 1-1/2 pounds a week. I think that a lot of people are not informed about the outcome. They spend $$$$$$ to lose the weight, but, they can’t stop. Usually your Dr. will put you on a maintenance dose. Again, stopping cold turkey is only going to turn into a weight gain.
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I hear your frustration, @ozzieandeva2025. Your experience echoes mine with switching and gaining weight back.
One thing my doctor mentioned to me yesterday is that sometimes people who don't lose weight on tirzepatide (Zepbound) often do better losing weight if they start doing the injections in their arms instead (in the arm location mentioned on the paperwork for the shots).
I have had to return to some previous clothes, but I also donated a number of clothes in my former size a year ago. How have you managed the regain and clothing, ozzieandeva2025?