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Prolia then Evenity?

Osteoporosis & Bone Health | Last Active: Jun 30 10:08am | Replies (12)

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I would start with Evenity (or another anabolic like Tymlos or Forteo) if that's an option as it builds up bone density to improve your numbers, before you go on something to "hold steady". I believe Evenity can be taken for one year. Be cautious starting Prolia so young until they find a way to successfully go off Prolia and avoid its rebound effect when you stop taking it (they are doing a lot of studies on it currently so hopefully they'll have some more definitive options in the near future). I didn't qualify for Evenity (my insurance wouldn't approve it), so I started with Tymlos (an anabolic bone building medication). My spinal bone density increased almost 20% on Tymlos. I then had an annual Reclast infusion to "lock in the gains"). I will have two more annual Reclast infusions, then go off drugs for a few years since it stays in your system for some time. I will have bone marker testing done while on the "drug holiday" to determine when it's time for the next step. Evenity may be in my future someday. I was 51 when diagnosed, now 54 so I have a long road of osteoporosis drugs in my future - the order they are taken in matters. My mom is on Prolia, she's in her 80's however so at this point they are planning to keep her on it for the rest of her life (unless they can find a definitive way to avoid the rebound effect). It can be great for protecting from breaks with a twice yearly injection, however, if too long on it, it eventually can cause issues (as all the meds can) and coming off of it can be a challenge. Good luck!

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Replies to "I would start with Evenity (or another anabolic like Tymlos or Forteo) if that's an option..."

Thanks so much for your long reply, @misst1970 ! So grateful your sharing and expertise. It seems I cannot begin with an anabolic because of my recent invasive breast cancer and the aromatase inhibitor 5year period. My bone doctor feels that Prolia is best to combat the AI effects on my bone density. So — Prolia for just 3 years, and then move on to Evenity. I’m anxious about adding more medication to treat the effects of my current medication, but since I’m at high risk of vertebral fracture (don’t even want to know how debilitating that might be), it seems I have no choice.
Thank you, thank you!!