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I participated in a Mayo prostate cancer support group webcast last month about proctectomy surgeries. At the end of the webcast someone asked a general question about using estrogen with or in lieu of ADT (sorry I can't remember exactly how the question was posed).
For what it's worth, the webcast presenter, a Mayo surgeon, replied along the lines of, "We no longer use estrogen in that manner." This caught my attention because I had read about estrogen being used in lieu of ADT a while ago.
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Hmmm.
Did the surgeon go on to explain why?
Besides the PATCH trial, I recall, albeit with a 69 year old mind literature on studies and use here in the US.
I hold my medical team to the same standards I hold myself when it comes to discuss treatment options, what's your reasoning and supporting "literature (aka, research) supporting that.
From my foxhole, making a statement like you describe is reason in my mind to say, hmmm, would I go with this person as a member if my medical team? The answer, likely not.
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There’s actually two possible uses for estrogen. One is to replace ADT the other as an adjunct to ADT.
Adding estrogen in a small dose increases the sex drive, which is almost eliminated by ADT. Usually, your body has some estrogen, but it’s normally hard to find if you’re on ADT. This exact issue was discussed in a recent prostate cancer bi monthly meeting where a GU oncologist answers questions for the first hour and discussed the use of some estrogen for that purpose.