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Skin squamous cell carcinoma (recurring)

Melanoma & Skin Cancer | Last Active: 3 days ago | Replies (114)

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@grammato3

@cicihi4 Thank you once again for the helpful information! I did some more research to find that Intralesional 5-Fluorouracil is "an antimetabolite that inhibits DNA synthesis in rapidly dividing cells, including those in cancers. By disrupting DNA production, it causes these cells to undergo apoptosis (programmed cell death) and necrosis (tissue death). Additionally, 5-FU can stimulate the immune system to target cancer cells. When administered intralesionally [the spaces in between], it delivers a high concentration of the drug directly to the target area while minimizing systemic exposure and potential adverse effects". This has primarily been used in dermatology for specific skin conditions, including actinic keratosis - rough, scaly patches that can be pre-cancerous.

So in getting back to your original question, I'll put this out there: Has anyone been aware of receiving Intralesional 5-Fluorouracil as treatment for skin conditions -- and, if so, what has your experience been?

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Replies to "@cicihi4 Thank you once again for the helpful information! I did some more research to find..."

I was diagnosed with SCC last year and have had ongoing MOHS surgeries.
I depend on my Dermatologist working with my Oncologist. I am currently infused with Libtayo every 3 weeks, visit with oncologist on a regular basis as well as my Dermatologist.
I also have had two pet scans and the SCC is on the left leg, primary the shin area.
I need to take a moment to "Thank" you volunteers!
They recommended me to "Wound Care",
It has been my lifesaver. I can't tell you how wonderful they are and how much faster my open wounds have healed.
Been getting infusions since last October, no major side effects.