@gus0557 Gus, unfortunately you are 100 percent correct. Once the damage is done it is done and the best we can hope for is to slow down progression. I have axonal PN and Mayo said the damage can't be reversed. Increased numbness has caused poor balance yet, I'm trying to walk as much as possible, and my numbness has remained mostly below the knees and small amount in fingertips. I'm now almost ten years into this and no answers. Ed