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ketruda and diabetes

Melanoma & Skin Cancer | Last Active: 3 days ago | Replies (6)

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@ronsale

Yes, I have had an issue. Blood work done before each infusion has shown all levels normal. However, skin rash and sores and itching have now become intolerable. I stopped infusions about two months ago because of skin condition, and my next infusion is scheduled for later in June. However, all the skin problems remain and seem to be getting worse. So, I have decided that after blood work and visiting with doctor I will just stop. I have had 14 infusions in the last 14 months, and I think it is time to stop Keytruda before I get some more side effects.

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Replies to "Yes, I have had an issue. Blood work done before each infusion has shown all levels..."

Is the keytruda itch all over your body? I am currently on a regime of Carboplatin, Taxol, and keytruda and had a very severe itch in my feet and hands. It has mostly resolved with a 100mg of Gabapentin taken 3x/day. I am hoping this is not a permanent state of being. I sit down and elevate my feet when they start to itch, if I was working it would be impossible.
The 1/2 life of Keytruda is 22 days, so at 22 days 1/2 of it is still circulating, at 44 days 1/4 would be left. I imagine with repeated infusions the numbers are a lot higher and it will take awhile to clear it out of your system.