Not quite sure what you are saying. You say your T recovered to 400+, But then you say “ If T is 155 now”. I guess that just a hypothetical?? If your T is stuck at 155 and considering TRT! Some people do it without a problem, Some people have their PSA rise. I think I saw somebody posted that in here a month or so ago. You might go to the top level of Mayo prostate cancer and search for testosterone and find more comments.

Prostate cancer feeds on testosterone even after you become castrate resistant because not all of the cancer is castrate resistant, so ADT works on some of it. This is one of the things I face.

It took 3 1/2 years after my surgery before prostate cancer came back again. Sound familiar? 2 1/2 years later, it came back again and I had salvage radiation.

Neither of us are unusual, PC comes back a lot after surgery. In my case, I have BRCA2 so it’s difficult for my cells to prevent prostate cancer from propagating. In your case, you had an advanced case that required triplet therapy (chemotherapy). That means that the cancer is in your bloodstream and can go anywhere, and come back anywhere. You may end up having to be on these drugs for a lifetime in order to manage the cancer. We are both waiting for the drug that solves this completely.

The graph that you posted at the bottom is cut off on the right side in December of 2024. You don’t clearly say when you stopped ADT