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I was in a very similar situation as you except I had a 3+4/ 7 Gleason with a family history of prostate cancer. A PSMA test showed no spread. When my PSA got to 4.5, I had RP. I had a positive margin. My PSA after surgery started at .02 and slowly crept up to .17. Some folks consider "undetectable" as any PSA score less than .1. I don't - to me any score no matter how low is detectable. That said my PSADT was less than a year so I chose (after securing multiple opinions) to take 6 months of Orgovyx and RT to the prostate bed and lymph nodes at approximately one year after my RP. I am now undetectable (< .006) and hoping it continues to stay at this level for a long time. I do have some manageable incontinence and ED issues. I'm grateful for the early success and comforted that I chose the aggressive path I did. Good luck. There is no looking back.

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Replies to "I was in a very similar situation as you except I had a 3+4/ 7 Gleason..."

@jaacm1 You mentioned you have manageable incontinence and ED. I also have these issues following RP surgery and I never fully recovered. As I'm considering ADT, I've read that it could have significant side effects regarding incontinence and ED. Was your incontinence and ED a result of your RP surgery, or did it happen after starting Orgovyx? If it was a result of RP, did it get worse after starting Orgovyx?