Scientific Discoveries
A key scientific advancement this week is the discovery of unusual carbon build-up in the lungs of COPD patients, published on June 10, 2025, by the European Respiratory Society ScienceDaily - "Unusual carbon build-up found in lungs of COPD patients". The study, detailed in ERJ Open Research, involved 28 COPD patients and 15 smokers without COPD, revealing that alveolar macrophage cells in COPD patients contained over three times as much soot-like carbon. This carbon accumulation was linked to larger cell sizes and increased inflammation, correlating with worse lung function (measured by FEV1%). The findings suggest that pollution and carbon build-up, beyond smoking, may drive COPD, raising questions about carbon clearance ability in affected patients and potential links to particulate matter exposure. This discovery could shift research focus toward environmental factors and inspire new therapeutic strategies.
https://www.sciencedaily.com/releases/2025/06/250610230533.htm

Here is what has been happening with COPD treatment, research & developments in June 2025

June 10, 2025
Carbon build-up in COPD lungs Study shows over three times more carbon in COPD patients' lung cells, linked to inflammation and worse lung function New insight into COPD etiology, potential for new research
https://www.sciencedaily.com/releases/2025/06/250610230533.htm
June 13, 2025
New COPD research grant
$120,000 grant by CHEST and ALA for studies on care barriers, cessation, digital tools Could drive future innovations in COPD management
https://www.lung.org/blog/mission-moment-6-25
June 11, 2025
EpiEndo publishes glasmacinal data
Clinical/preclinical data support glasmacinal as a potential COPD treatment New treatment option with anti-inflammatory properties
https://www.epiendo.com/en/news-events/clinical-and-pre-clinical-data-on-the-novel-barriolide-ep395-glasmacinal-published-in-three-articles-in-pulmonary-pharmacology-and-therapeutics
June 9, 2025
Olympus launches AI emphysema screening (SeleCT™)
AI program reviews CT scans for early emphysema detection Improves early diagnosis and treatment access
https://www.biospectrumasia.com/news/50/26181/olympus-announces-full-market-release-of-ai-powered-emphysema-screening-programme.html
June 2, 2025
New COPD diagnostic schema Reclassifies patients with higher risk outcomes, published in JAMA Enhances risk stratification for better care
https://jamanetwork.com/journals/jama/fullarticle/2834253?guestAccessKey=0398b61f-6807-45b2-9dc7-71c2fd34136f
June 9, 2025 BREATHE Trial results
Six-month data on airway scaffolds for emphysema, published in May Promising new interventional therapy, ongoing relevance
Main results: Clinically meaningful improvements were further observed in spirometry, quality of life, symptoms and exercise capacity.
Conclusions: This study provides the first clinical evidence of the feasibility, safety and initial outcomes after treatment with airway scaffolds in patients with emphysema-related hyperinflation.
Clinical trial registration available at http://www.Clinicaltrials: gov, ID: NCT05949645, NCT05854550.
https://pubmed.ncbi.nlm.nih.gov/40387356/

as always like your infos and energy
why don't we try ourselves to raise enough money for a final step
there are 600 million of us, only say 10 million giving minimum 10 dollars as a price for a cure - which i am sure exists in a drawer somewhere a chance for someone to go ahead of the field and become famous.