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My ADT Story, Feedback Appreciated

Prostate Cancer | Last Active: Jun 19 9:41am | Replies (34)

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If ADT "buys me extra years", wouldn't I want to stay on it? Seems to me the complications from ADT would be worth the extra time? I'm confused and don't understand why my Drs would think it better for me to stop? I've had no adverse side effects from Orgovyx and whatever they are or may be can't be as bad as my cancer coming back or spreading?

My Drs have taken an aggressive approach-- surgery+radiation+ADT, because the cancer has aggressive characteristics (Gleason and Decipher). I'm happy with the outcome so far. I'm just scared and don't understand why they're wanting me off the ADT.

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Replies to "If ADT "buys me extra years", wouldn't I want to stay on it? Seems to me..."

They might want you to stop because while ADT can help hold off cancer progression, it increases your risk of diabetes, osteoporosis, and heart disease, and can also put a strain on your kidneys. In my case, with stage 4b to my bones, they figure that the cancer-progression risk outweighs the others (plus my bloodwork and other tests show that I'm tolerating Orgovyx and Erleada well as the end of year 4 gets nearer); in yours, they might figure that the immediate risk of progression is smaller, so it might be worth giving the rest of your body a little break.

While there are studies supporting ADT holidays for earlier-stage prostate cancer right now, it's still as much an art as a science trying to balance all those risks for each individual patient. I told my care team right at the start that I was all-in for fighting the cancer (age 56 then, previously fit and healthy except for mild hypertension), and they've respected that wish by "throwing the kitchen sink at it," as they described it.