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My ADT Story, Feedback Appreciated

Prostate Cancer | Last Active: 4 hours ago | Replies (27)

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@northoftheborder

"I've read that castrate resistance typically occurs within 2-3 years of going on ADT. Resistance is defined as the PSA rising while on ADT. And like I said in my initial post, if the cancer becomes castrate resistant, I've read the prognosis is not good."

Yes, but I'm pretty sure that number refers to cases where the cancer is active and would have already been progressing during those 2-3 years without ADT (e.g. stage 4). The ADT buys you those extra years before progression, and with extra help (e.g. radiation, ARSI, chemo), may sometimes postpone it indefinitely.

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Replies to ""I've read that castrate resistance typically occurs within 2-3 years of going on ADT. Resistance is..."

If ADT "buys me extra years", wouldn't I want to stay on it? Seems to me the complications from ADT would be worth the extra time? I'm confused and don't understand why my Drs would think it better for me to stop? I've had no adverse side effects from Orgovyx and whatever they are or may be can't be as bad as my cancer coming back or spreading?

My Drs have taken an aggressive approach-- surgery+radiation+ADT, because the cancer has aggressive characteristics (Gleason and Decipher). I'm happy with the outcome so far. I'm just scared and don't understand why they're wanting me off the ADT.