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My ADT Story, Feedback Appreciated
Prostate Cancer | Last Active: 12 hours ago | Replies (27)Comment receiving replies
Thank you for the insight.
I've read that castrate resistance typically occurs within 2-3 years of going on ADT. Resistance is defined as the PSA rising while on ADT. And like I said in my initial post, if the cancer becomes castrate resistant, I've read the prognosis is not good.
Right now, there's no metastasis that we know of. I sure wouldn't want coming off ADT to cause or speed up cancer spread.
To me, staying on ADT and risking those complications is better than having cancer recur. But, I'm told that ADT isn't going to stop spread? (So, why am I taking it?) But I know with my Gleason and Decipher both very high that my cancer is aggressive and the odds of recurrence is high.
I don't think my doctors will approve me going more than 3 years on ADT. So, it would be nice to know my options should my PSA rise. Seems risky to me to come off-- but they say say resistance and spread can happen either way......... 🙁
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"I've read that castrate resistance typically occurs within 2-3 years of going on ADT. Resistance is defined as the PSA rising while on ADT. And like I said in my initial post, if the cancer becomes castrate resistant, I've read the prognosis is not good."
Yes, but I'm pretty sure that number refers to cases where the cancer is active and would have already been progressing during those 2-3 years without ADT (e.g. stage 4). The ADT buys you those extra years before progression, and with extra help (e.g. radiation, ARSI, chemo), may sometimes postpone it indefinitely.