I've experienced increasing pain with each treatment. I've just finished my 5th of a 6 treatment routine. The 4th was very painful, the 5th was nearly debilitating. After the 4th I asked the urologist for a script for pain meds. He refused saying just use the Uribel and tylenol, which barely puts a dent into pain reduction. I also tried pyridium and it seemed less effective than Uribel. Docs are so afraid to prescribe pain meds it seems. He says his other bcg patients don't have the problem but searching on line shows him to be wrong. Some even reported pain even a year or more after their last treatment. I wonder if Tylenol w/ codine might help and be acceptable?