I'm sorry you're going through this. I know it's frustrating when the first line of defense doesn't work as you hoped it would. It sounds like they are indicating that there has been progression or feowth of the tumor since your last scan. It would seem that you may need to consider other treatment options. Fortunately there are many. Captem (a combination oral chemo of capcetibine and temodar) is an often used option.
I'm not sure if I fully understand your question about the veins, but if you're wondering about a tumor encroaching into a vein, that can sometimes make surgery difficult. If that's the case, then captem may shrink the tumor to make surgery viable. There are also many other treatment options, including non systemic liver directed therapies such as embolization.
Where are you located? Are you currently seeing a net specialist?

Wow. Interesting. Thanks Susan. Sounds pretty complicated.