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Fun with ADT and testosterone

Prostate Cancer | Last Active: 4 days ago | Replies (15)
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@jeffmarc

Those pubmed articles show 53% still at castrated Testosterone levels after 31 months. And they didn’t spend 8 years on ADT and I am 77.

At the rate I have been rising I would be Over 200 in less than 16 months.

My cancer is very aggressive, I went from PSA of .2 to 1 in 18 days when I tried to go from 4 Zytiga to 3, and I was also on Lupron. I can’t take a chance of having my testosterone rise So back on Orgovyx.

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Replies to "Those pubmed articles show 53% still at castrated Testosterone levels after 31 months. And they didn’t..."
pjsatz | @pjsatz | 6 days ago

I think i saw that you were also on darolutamide. Will you be on darolutamide and Orgovyx now? Was thinking darolutamide would be enough to slow the psa but sounds like it is not. All the best with it, of course.

Thanks,

Phil

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brianjarvis | @brianjarvis | 6 days ago

Yes, other studies have similar results. More than just a few years on ADT and being upward in years, sometimes makes those T recovery guidelines a bit more fuzzy.

Might be one of the reasons they’re moving doublet therapy (ADT+ARPI) up earlier into the treatment regimen.

Catching it early is key,

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