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Darolutamide Monotherapy

Prostate Cancer | Last Active: 3 days ago | Replies (9)

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@mmacaulay

You might want to fact check what you said. It was darolutamide that was approved for monotherapy (on June 5th). The point I was trying to make is that Nubeqa alone (as well as other androgen blockers) might provide advantages over prolonged ADT because it allows for increased T. And therefore less genetic pressure on mutation to castration resistance.

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Replies to "You might want to fact check what you said. It was darolutamide that was approved for..."

I think the problem here is that Darolutamide is not capable of overcoming all testosterone levels. It can for a while, but my oncologist specifically told me that once the testosterone got over around 250 Darolutamide had issues with keeping the PSA down.

Testing will show what’s real.