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DiscussionThe Gray Area of Favorable Intermediate Risk 3+4=7
Prostate Cancer | Last Active: 3 days ago | Replies (35)Comment receiving replies
Replies to "Thx for the comments as I too am a Gleason 7 (3+4), 10%, 1 lesion in..."
Your statistics are very much like mine were. I chose focal therapy with the objective of trying to balance efficacy of treatment with quality of life/side effects. While there isn't a decision tree to help choose the modality of treatment, one of the key parameter/requirements should be accuracy/precision of treatment. I would rule out anything that isn't in-bore, MRI directed, in real time. I chose TULSA-PRO for those reasons, although I am of the understanding that cryotherapy is also possible under MRI real time direction. Beyond that it is critically important that the procedure be performed at a center of excellence, best done in a hospital setting, and by a doctor who is highly experience in targeting. You want precision (good margins), you want something other than a store front (center of excellence) and you want someone who really knows what they're doing and has significant experience in having done it. That's what maximizes your odds for a favorable outcome in my opinion.
Excellent point about focal therapies as 3+4=7 with certain types of lesions tend to make the best candidates. My surgeon does cryotherapy and we discussed it as an option. And it's covered by insurance. He told me that the effectiveness is less than surgery or radiation and it doesn't remove future potential lesions. But options for additional treatment remain.
Did you choose a focal therapy? Which?