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Salvage radiation decision: with or without hormone therapy?
Prostate Cancer | Last Active: Jul 30 6:54am | Replies (58)Comment receiving replies
Having just finished SRT at Sloan I would advise radiation to the prostate bed AND pelvic lymph nodes - 30% failure rate in SRT comes from neglecting the lymph nodes.
Also, I chose to have 6 months ADT (even after another RO said it was not necessary) to give me a chance at a better outcome - no matter what all the ‘experts’ say about it being overtreatment. How many freakin times do I wanna play with this?!
You will ultimately decide what’s best for you; I was G4+3 unfavorable at surgery so I knew I was dealing with a tougher strain of PCa and I wanted to hit it hard. Only time will tell if I will succeed. Best,
Phil
Replies to "Having just finished SRT at Sloan I would advise radiation to the prostate bed AND pelvic..."
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i think that's right ,Phil.
I found this on AI
Yes, when considering salvage radiation therapy (SRT) with androgen deprivation therapy (ADT) for recurrent prostate cancer, a 5-year freedom from biochemical progression rate as high as 87.4% has been reported in a phase 3 randomized controlled trial. This study, the SPPORT trial, evaluated SRT to the prostatic bed and pelvic lymph nodes, combined with a short course of ADT. This was the experimental arm in the study, and it showed a higher freedom from progression rate compared to SRT to the prostatic bed with ADT (81.3%) or SRT alone (70.9%). The SPPORT trial indicated that SRT plus ADT offered a benefit in progression-free survival.